Understanding the residential end uses of water is helpful for the sustainable management of water resources and the implementation of water conservation strategies. In this study, over one hundred studies were systematically reviewed to provide a comprehensive overview of the state-of-the-art research on end-use water consumption. Each study was reviewed, clustered, and subjected to a multilevel analysis aimed at quantitatively comparing the characteristics of the end uses of water available in the literature. The findings of this work support water utilities, researchers, policy makers, and consumers in identifying the key aspects of water end uses and exploring their main features across different geographical, socioeconomic, and cultural regions of the world.